Case Report
Chronic Invasive Nongranulomatous Fungal Rhinosinusitis in Immunocompetent Individuals
Table 1
Characteristics and outcome of the patients.
| | Case | Case | Case | Case |
| Age/gender | 58 yrs/male | 43 yrs/male | 60 yrs/female | 68 yrs/male | Immune suppression | − | − | − | − | Symptom onset to diagnosis | 6 months | 24 months | 9 months | 6 months | Symptoms at presentation | Left orbital pain | Nasal obstruction | Dizziness | Headache | Swelling on the face | Headache | Headache | Left retroorbital pain | Nasal obstruction | Facial pain | Postnasal drip | | Anatomic subsite involvement | | | | | Nasal cavity | + | + | − | − | Osteomeatal complex | + | + | − | − | Maxillary sinus | + | − | − | − | Ethmoidal sinuses | + | + | + (right posterior) | + (right posterior) | Sphenoid sinus | + (left side) | + (left side) | + (right side) | + (right side) | Frontal sinus | + | + | − | − | Bilateral involvement | − | − | − | − | Orbital involvement | LP destruction | LP destruction | − | − | Intracranial extension | − | − | + | − | Surgical treatment | ESS | ESS combined with external frontal sinus surgery | ESS | ESS | Organism | | | | | Microbiology | A. fumigatus | A. flavus | A. fumigatus | − | Histopathology | Nongranulomatous CIFRS | Nongranulomatous CIFRS | Nongranulomatous CIFRS | Nongranulomatous CIFRS | Medical treatment | | | | | Voriconazole | + | + | + | + | Follow-up time | 10 months | 8 months | 7 months | 5 months | Disease recurrence | − | − | − | − |
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LP: lamina papyracea, ESS: endoscopic sinus surgery, and CIFRS: chronic invasive fungal rhinosinusitis.
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