Oncocytoma of the Submandibular Gland: Diagnosis and Treatment Based on Clinicopathology

Table 1

Summary of clinical characteristics of submandibular oncocytoma.

Case	Age (sex)	Signs/symptoms	Laterality	Size	Mode of diagnosis	Treatment	Follow-up
() Eneroth [12]	75 (F)	N/A	N/A	N/A	Aspiration biopsy	N/A	N/A
() Dibble and Sanford [13]	79 (M)	Asymptomatic, viral URI	Left	2 × 3 cm, grew to 5.5 × 3 × 2.5 cm	N/A	Excision via external method	N/A
() Mukai et al. [14]	61 (M)	N/A	Left	N/A	N/A	N/A	3 years, alive
() Goode and Corio [15]	60 (F)	N/A	Unknown	N/A	N/A	N/A
() Brandwein and Huvos [11]	62 (M)	N/A	Left	N/A	N/A	N/A	6 months, alive
() Ziegler et al. [16]	56 (F)	N/A	N/A	N/A	N/A	N/A	9 months, alive
() Thompson et al. 22 cases [3]	See descriptions below
() Nakada et al. [2]	68 (M)	Painless, enlarging mass	Left	7 × 4.5 cm	FNA	Radical resection	1.5 years, alive
() Sakthikumar et al. [17]	19 (F)	Painless to dull ache	Left	3 × 5 cm	FNA	Excision	8 weeks, comfortable
() Subramaniam et al. [18]	85 (M)	Asymptomatic	Left	12 mm	F18 FDG PET/CT	N/A	N/A
() Dastaran and Chandu [19]	61 (F)	MEN2B, NF1 Long-standing mild tenderness	Bilateral	N/A	Ultrasound, FNA	Bilateral excision	1 year, no recurrence
() Chen et al. (present case)	63 (M)	Tender mass	Right	1.6 × 1.3 cm	FNA, CT	Excision	1 year, no recurrence

Thompson et al. [3] presented 22 cases of submandibular oncocytoma with 50 : 50 female-to-male ratio and an average age of 59 years. Sizes of the tumor ranged from 0.7 cm to 7 cm, averaging 3 cm. More than half of the cases (13/22) involved enlarging asymptomatic painless masses whereas the rest involved tender masses. On follow-up, none of the cases had evidence of recurrent disease.