Case Report

An Unusual Presentation of B-Cell Lymphoma as a Large Isolated Epiglottic Mass: Case Report and Literature Review

Table 1

Details of the immunostaining and hybridization: immunohistochemistry.

Immunostaining/ISH

1CD3Scattered small T-lymphocytes positive
2CD10Lymphoma negative
3CD20Lymphoma positive
4CD21Rare partially disrupted follicular dendritic cell networks highlighted
5CD23Negative
6CD43Negative with scattered small lymphocytes positive
7BCL2Positive
8BCL6Positive (45% in a cell count of 200)
9MUM1Positive
10Cyclin D1Negative
11C-MYCNegative
12KappaExtremely rare plasma cells positive
13LambdaExtremely rare plasma cells positive
14Ki67Low proliferation rate in majority of lymphoid infiltrate (approximately 10% cells in cycle overall); one focus with extensive crush artifact demonstrates increased proliferation rate (~20–30%)
15EBER ISHNegative

Performed at LAC + USC Medical Center Immunohistochemistry Laboratory.