Lymphoepithelial Carcinoma Originated from the Sinonasal Cavity: Case Report and Literature Review

Figure 3

Photomicrographs of the nasopharyngeal biopsy showing (a) infiltrative malignant neoplasm admixed with mixed chronic inflammatory cell infiltrate (H&E stain; 10x); (b) tumor cells with moderate amphophilic cytoplasm, vesicular nuclei, and prominent nucleoli; (c) lymphoplasmacytic cell infiltrate (arrow; H&E stain; 20x), with tumor cells showing cytoplasmic positivity for CK8/18 (IHC; 20x); (d) tumor cells with nuclear positivity for EBER (in situ hybridization for Epstein–Barr virus; 20x).