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Case Reports in Pediatrics
Volume 2012 (2012), Article ID 624168, 5 pages
Case Report

Mycophenolate Mofetil-Related Enterocolitis and Weight Loss: A Pediatric Case Series

1Division of Gastroenterology Hepatology and Nutrition, Cincinnati Children’s, 3333 Burnet Avenue MLC 2010, Cincinnati, OH 45229-3039, USA
2Division of Gastroenterology, University of Southern California, 4650 Sunset Boulevard, MS #126, Los Angeles, CA 90027, USA
3Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Vanderbilt University School of Medicine, 2200 Children's Way, 11th Floor, Doctors' Office Tower, Nashville, TN 37232-2576, USA
4Seacoast Pathology, Aurora Diagnostics, 1 Hampton Road, Suite 208, Exeter, NH 03833-4849, USA
5Division of Gastroenterology, Oschner Children’s Health Center, 1315 Jefferson Highway, New Orleans, LA 70121, USA
6Division of Pediatric Gastroenterology and Nutrition Sciences, University of Alabama at Birmingham, 1600 7th Avenue. S., Lowder Blgd., Ste. 618, Birmingham, AL 35233, USA
7Department of Nephrology, University of Minnesota, Pediatric Specialty Care Discovery Clinic, 2512 Building, 2512 S. 7th Street, Minneapolis, MN 55454, USA
8Division of Pediatric Nephrology, Vanderbilt University School of Medicine, 2200 Children's Way, 11th Floor, Doctors' Office Tower, Nashville, TN 37232, USA
9Department of Pathology, University of Arizona, 1501 N. Campbell Avenue, P.O. Box 245108, Tucson, AZ 85724-5108, USA

Received 10 August 2012; Accepted 6 September 2012

Academic Editors: E. Czkwianianc, A. W. Kamps, and D. I. Zafeiriou

Copyright © 2012 Dana M. H. Dykes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

This graphic demonstrates the weight-for-age percentiles in an adolescent with Wegener's granulomatosis and mycophenolate mofetil (MMF)-induced villous atrophy. (A) Patient diagnosed with Wegener's at age 8 years old. (B) At age 12, began MMF with a gradual increase in dosage . (C) Hospitalized at age 14 with severe diarrhea and failure to thrive. MMF is switched to enteric coated mycophenolate sodium and nasogastric supplemental feeds initiated. (D) Nasogastric feeds discontinued.

  1. Supplementary Material