|
Author/Year [Reference] | Gestational age, wk; (Birth wt, g) | Catheter type | Region and clinical findings | 2% nitroglycerin topical dose | Outcome |
|
Wong et al./1992 [37] | 25; (700), 24; (780) | (1) Right radial (2) Right radial | (1) No pulse, right hand blanched (2) no pulse, blue fingers, right hand rigid | Ribbon 4 mm/kg in both cases | (1) Improvement within 15 min, full recovery in 3 hr (2) Two doses with complete recovery after 16 hr except for 2 small blue areas. |
|
Varughese and Koh/2001 [38] | 33; (1870) | UAC | Ischemic changes over right hip. Normal femoral + popliteal pulses | 0.4 mg over 2 hr—twice | Improvement over 7 hr with complete resolution after 30 hr |
|
Baserga et al./2002 [39] | (1) 30; (1620) (2) 25; (not stated) (3) 23; (660) | (1) UAC (2) UAC (3) Left radial | (1) Poor perfusion left leg, weak femoral + tibial pulses (2) Right leg blanched, absent femoral pulse, cyanotic toes (3) Pale left hand and fingers, absent radial pulse | (1) 4 single applications over affected parts-dose not stated (2) 4 mm/kg—four single applications over affected parts (3) ribbon of ointment-dose not stated-3 single applications to affected areas | (1) Complete recovery in 45 min (2) Complete recovery in 45 min (3) Improvement in 30 min with full recovery. |
|
Vasquez et al./2003 [46] | 26; (896) | Left peripheral arterial line (location not stated) | Pale cyanotic left hand with discoloration from mid-palm to finger tips. | Ribbon 4 mm/kg q 8 hr for 27 days | Improvement in 8 hr with gradual recovery over 18–27 days. No deficit at 8 months. |
|