Case Report

Membranoproliferative Glomerulonephritis and X-Linked Agammaglobulinemia: An Uncommon Association

Table 1

Patients with XLA and renal disease due to immune complex deposition.

ReferenceAgePresentationRenal histologyTreatmentOutcome

Present case10 yearsPneumonia, macroscopic hematuria, and nephrotic proteinuriaMPGN type ISwitched immunoglobulin brand; corticosteroid therapyAsymptomatic with normal renal function and no proteinuria and improved hematuria

Yoshino et al., 2006 [5]3 yearsMicroscopic hematuria, nephrotic proteinuria, and low serum complementMPGN type IIISwitched immunoglobulin brand; corticosteroid therapyAsymptomatic with normal renal function and improved hematuria and proteinuria

Endo et al., 2011 [6]23 yearsMicroscopic hematuriaMembranous glomerulopathySwitched immunoglobulin brandAsymptomatic with normal renal function and minimal proteinuria