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Case Reports in Pediatrics
Volume 2015 (2015), Article ID 537530, 4 pages
http://dx.doi.org/10.1155/2015/537530
Case Report

Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging

1Department of Pediatric Hematology-Oncology, İstanbul Kanuni Sultan Süleyman Educational and Research Hospital, 34303 Istanbul, Turkey
2Department of Pediatric Hematology-Oncology, Faculty of Medicine, Acıbadem University, 34742 Istanbul, Turkey
3Department of Pediatric Rheumatology, İstanbul Kanuni Sultan Süleyman Educational and Research Hospital, 34303 Istanbul, Turkey
4Department of Radiology, İstanbul Kanuni Sultan Süleyman Educational and Research Hospital, 34303 Istanbul, Turkey
5Department of Radiology, İstanbul Faculty of Medicine, İstanbul University, 34093 Istanbul, Turkey
6Department of Pathology, İstanbul Faculty of Medicine, İstanbul University, 34093 Istanbul, Turkey

Received 28 April 2015; Revised 30 July 2015; Accepted 6 August 2015

Academic Editor: Jonathan Muraskas

Copyright © 2015 Gonca Keskindemirci et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Kasabach-Merritt phenomenon (KMP) is characterized by vascular tumour and consumptive coagulopathy with life-threatening thrombocytopenia, prolonged prothrombin time and partial thromboplastin time, hypofibrinogenemia, and the presence of high fibrin split products. We report a case of 3-year-old boy with local aggressive vascular lesions associated with KMP. Magnetic resonance imaging revealed an extensive lesion at paravertebral and retroperitoneal regions that was infiltrating vertebrae. Although we did not get any response to steroid or propranolol treatment, partial response was observed radiologically with interferon-alpha treatment. Unfortunately, the patient died because of the uncontrolled consumptive coagulopathy that led to intracranial hemorrhage which was caused by huge knee hematoma after minor trauma.