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Case Reports in Pediatrics
Volume 2015, Article ID 615368, 3 pages
http://dx.doi.org/10.1155/2015/615368
Case Report

Bladder Wall Telangiectasia in a Patient with Ataxia-Telangiectasia and How to Manage?

Department of Pediatric Infectious Diseases, Clinical Immunology and Allergy, Istanbul University, Cerrahpasa Medical Faculty, 34098 Istanbul, Turkey

Received 19 September 2015; Revised 8 November 2015; Accepted 19 November 2015

Academic Editor: Mohammad Ehlayel

Copyright © 2015 Fatma Deniz Aygün et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Ataxia-telangiectasia (A-T) is a rare neurodegenerative, inherited disease causing severe morbidity. Oculocutaneous telangiectasias are almost constant findings among the affected cases as telangiectasia is considered the main clinical finding for diagnosis. Vascular abnormalities in organs have been reported infrequently but bladder wall telangiectasias are extremely rare. We aimed to report recurrent hemorrhage from bladder wall telangiectasia in a 9-year-old boy with A-T who had received intravenous cyclophosphamide for non-Hodgkin’s lymphoma. Since A-T patients are known to be more susceptible to chemical agents, we suggested that possibly cyclophosphamide was the drug which induced bladder wall injury in this patient.