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Case Reports in Pediatrics
Volume 2016, Article ID 2329483, 6 pages
Case Report

Use of Zoledronic Acid in Paediatric Craniofacial Fibrous Dysplasia

1Department of Women’s and Children’s Health, University of Padua, 3 Giustiniani Street, 35128 Padua, Italy
2Pediatric Pain and Palliative Care Service, University of Padua, 59 Ospedale Civile Street, 35121 Padua, Italy
3Department of Medical and Surgical Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
4Rehabilitation Section, Department of Neuroscience, University of Padua, Via Giustiniani 2, 35128 Padua, Italy

Received 11 May 2016; Accepted 28 August 2016

Academic Editor: Yann-Jinn Lee

Copyright © 2016 Chiara Di Pede et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We describe a case of a paediatric patient affected by mandibular fibrous dysplasia (FD) with severe and chronic pain who was successfully treated with zoledronic acid (ZOL): a third-generation bisphosphonate. Further research is needed to assess its safety and efficacy as a treatment option for FD in the paediatric population.