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Case Reports in Pediatrics
Volume 2016, Article ID 4048501, 3 pages
Case Report

Cystic Lung Disease in Down Syndrome: A Case Report and Literature Review

SUNY Downstate Medical Center, Department of Pediatrics, 450 Clarkson Avenue, Brooklyn, NY 11203, USA

Received 15 July 2016; Accepted 15 September 2016

Academic Editor: Juan Manuel Mejía-Aranguré

Copyright © 2016 Mathew George et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Subpleural lung cysts (SPC) are seen in children with Down syndrome (DS). The incidence and the long term course of these lesions are not known. It is important for pediatricians and pediatric radiologists to be aware of these lung lesions since the DS patients’ longevity has increased and they have greater frequency to encounter the clinicians. Autopsy and the radiology series have shown that these lesions are often found in association with congenital heart disease, particularly the endocardial cushion defect and prematurity.