A Fatal Case of Congenital Langerhans Cell Histiocytosis with Disseminated Cutaneous Lesions in a Premature Neonate

Table 1

Outcomes of premature neonates with congenital cutaneous LCH lesions at birth.

Author (reference number)	Gender	GA (wks)	Clinical features of LCH involvement	Outcome (survival)
Vade et al. [10]	F	35	Skin, hepatosplenomegaly, pulmonary failure	Died (9 days)
Gee et al. [11]	M	33	Skin, pulmonary failure	Died (36 hrs)
Aviner et al. [12]	F	32	Skin, followed by multiorgan failure	Died (26 days)
Lee et al. [8]	M	36	Hydrops fetalis, skin, multiorgan failure	Died (12 days)
Cheng et al. [9]	M	33	Hydrops fetalis, skin, pleural effusion	Died (36 hrs)
Herbrüggen et al. [13]	M	35	Skin, at 3 months, pulmonary and thymic mass	Alive
Present case	F	33	Skin, hypovolemic shock, pulmonary failure	Died (57 hrs)

GA: gestational age, M: male, F: female, wks: weeks, and hrs: hours.