Case Report
Resolution of Periodic Breathing in a Child with Idiopathic Pulmonary Arterial Hypertension
Table 1
PSG results of the patient before and after treprostinil and oxygen therapy.
| | Results | At diagnosis | After treprostinil |
| | TST, min | 338 | 269.5 | | Sleep latency, min | 11.4 | 6.4 | | Sleep efficiency, % | 67.3 | 70.8 | | REM latency, min | 276.5 | 136.5 | | Stage N1, %TST | 24.9 | 7.4 | | Stage N2, %TST | 46 | 57 | | Stage N3, %TST | 24.4 | 28.2 | | REM, %TST | 4.7 | 7.4 | | Arousals, total index | 23.1 | 9.1 | | Mean sleep SpO2 (%) | 93 | 95 | | Minimum SpO2 (%) | 57 | 90 | | Desaturation Index (events/hr) | 15.7 | 0.5 | | Highest TcCO2/etCO2 (mmHg) | 45 | 46 | | Mean TcCO2/etCO2 (mmHg) | 32 | 39 | | OAHI (events/hour) | 0 | 0 | | CAHI (events/hour) | 6.3 | 0.5 | | RVSP (estimated) | Suprasystemic | <1/2 systemic | | NT-proBNP (pmol/L) | 147 | 12 | | 6MWT (meters) | 380 | 660 | | Mean SpO2 during wakefulness (%) | 94 | 99 | | Mean TcCO2/etCO2 during wakefulness (%) | 30 | 35 |
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TST: total sleep time, REM: rapid eye movements, SaO2: oxygen saturation, TcCO2: transcutaneous carbon dioxide, etCO2: end tidal carbon dioxide, OAHI: obstructive apnea-hypopnea index, CAHI: central apnea-hypopnea index, RVSP: right ventricular systolic pressure, NT-proBNP: N-terminal pro b-type natriuretic peptide, and6MWT: 6-minute walk test.
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