Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Pediatrics
Volume 2017, Article ID 5184587, 3 pages
https://doi.org/10.1155/2017/5184587
Case Report

Evans Syndrome Complicated by Intratubular Hemoglobin Cast Nephropathy

The Lauren V. Ackerman Laboratory of Surgical Pathology, St. Louis Children’s Hospital, Washington University Medical Center, St. Louis, MO, USA

Correspondence should be addressed to Iván González; ude.ltsuw@izelaznog

Received 27 July 2017; Accepted 14 September 2017; Published 15 October 2017

Academic Editor: Giovanni Montini

Copyright © 2017 Iván González et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Aladjidi, H. Fernandes, T. Leblanc et al., “Evans Syndrome in Children: Long-Term Outcome in a Prospective French National Observational Cohort,” Frontiers in Pediatrics, vol. 3, pp. 1–8, 2015. View at Publisher · View at Google Scholar
  2. M. Michel, V. Chanet, A. Dechartres et al., “The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases,” Blood, vol. 114, no. 15, pp. 3167–3172, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. M. A. Khalighi, K. J. Henriksen, A. Chang, and S. M. Meehan, “Intratubular hemoglobin casts in hemolysis-associated acute kidney injury,” American Journal of Kidney Diseases, vol. 65, no. 2, pp. 337–341, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. L. B. De Sanctis, M. Mandreoli, C. Poggi, S. Pileri, S. Casanova, and A. Santoro, “Acute renal failure in a young woman with Fisher-Evan's syndrome,” Journal of Nephrology, vol. 17, no. 5, pp. 739–743, 2004. View at Google Scholar · View at Scopus
  5. C. Mammen, M. L. Bissonnette, and D. G. Matsell, “Acute kidney injury in children with sickle cell disease—compounding a chronic problem,” Pediatric Nephrology, vol. 32, no. 8, pp. 1287–1291, 2017. View at Publisher · View at Google Scholar
  6. S. Baddam, I. Aban, L. Hilliard, T. Howard, D. Askenazi, and J. D. Lebensburger, “Acute kidney injury during a pediatric sickle cell vaso-occlusive pain crisis,” Pediatric Nephrology, pp. 1–6, 2017. View at Publisher · View at Google Scholar · View at Scopus
  7. I. Al Ghaithi, N. A. M. Wright, V. R. Breakey et al., “Combined Autoimmune Cytopenias Presenting in Childhood,” Pediatric Blood & Cancer, vol. 63, no. 2, pp. 292–298, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Mendonca, S. Srivastava, R. Kapoor, D. Gupta, P. Gupta, and M. L. Sharma, “Evans syndrome and its link with systemic lupus erythematosus,” Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, vol. 27, no. 1, pp. 147–149, 2016. View at Publisher · View at Google Scholar · View at Scopus
  9. E. Oliveira Da Fonseca, A. Jittirat, K. A. Birdwell, and A. B. Fogo, “Myoglobin cast nephropathy in a kidney transplant patient with normal creatine kinase,” American Journal of Kidney Diseases, vol. 65, no. 4, pp. 628–631, 2015. View at Publisher · View at Google Scholar · View at Scopus
  10. H. E. Harrison, H. Bunting, N. K. Ordway, and W. S. Albrink, “The pathogenesis of the renal injury produced in the dog by hemoglobin or methemoglobin,” The Journal of Experimental Medicine, vol. 86, no. 4, pp. 339–356, 1947. View at Publisher · View at Google Scholar · View at Scopus
  11. S. R. Braun, F. R. Weiss, A. I. Keller, J. R. Ciccone, and H. G. Preuss, “Evaluation of the renal toxicity of heme proteins and their derivatives: A role in the genesis of acute tubule necrosis,” The Journal of Experimental Medicine, vol. 131, no. 3, pp. 443–460, 1970. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Paller, “Hemoglobin- and myoglobin-induced acute renal failure in rats: role of iron in nephrotoxicity,” American Journal of Physiology, vol. 255, pp. 539–544, 1998. View at Google Scholar
  13. Q. Qian, K. A. Nath, Y. Wu, T. M. Daoud, and S. Sethi, “Hemolysis and acute kidney failure,” American Journal of Kidney Diseases, vol. 56, no. 4, pp. 780–784, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. C. B. F. Andersen, M. Torvund-Jensen, M. J. Nielsen et al., “Structure of the haptoglobinhaemoglobin complex,” Nature, vol. 489, no. 7416, pp. 456–459, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. M. J. Tracz, J. Alam, and K. A. Nath, “Physiology and pathophysiology of heme: implications for kidney disease,” Journal of the American Society of Nephrology, vol. 18, no. 2, pp. 414–420, 2007. View at Publisher · View at Google Scholar · View at Scopus