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Case Reports in Pediatrics
Volume 2017, Article ID 6570465, 3 pages
https://doi.org/10.1155/2017/6570465
Case Report

Prenatal Diagnosis of Atrioventricular Block and QT Interval Prolongation by Fetal Magnetocardiography in a Fetus with Trisomy 18 and SCN5A R1193Q Variant

1Department of Child Health, University of Tsukuba, Tsukuba, Japan
2Department of Pediatric Cardiology, Ibaraki Children’s Hospital, Mito, Japan
3Department of Obstetrics and Gynecology, University of Tsukuba, Tsukuba, Japan

Correspondence should be addressed to Lisheng Lin; pj.ca.nimu@mah-nir

Received 17 February 2017; Accepted 2 May 2017; Published 30 May 2017

Academic Editor: Seyed Mohsen Dehghani

Copyright © 2017 Lisheng Lin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We report a case of fetal trisomy 18 with SCN5A R1193Q variant that presented with sinus bradycardia, 2 : 1 atrioventricular block (AVB), and QT interval prolongation. These complex arrhythmias were diagnosed by fetal magnetocardiography combined with ultrasound findings. Advanced AVB and ventricular arrhythmias were confirmed after birth. Genetic testing of the baby revealed a SCN5A R1193Q variant, which we considered could account for the various arrhythmias in this case.