Case Report

Neonatal Liver Failure and Congenital Cirrhosis due to Gestational Alloimmune Liver Disease: A Case Report and Literature Review

Table 2

Causes of neonatal liver failure excluded and assessment methods.

CauseAssessment method

SyphilisQuantitative nontreponemal serologic test
ToxoplasmosisSerology (IgG and IgM)
RubellaSerology (IgG and IgM)
CytomegalovirusSerology (IgG and IgM) and urinary PCR
Herpes simplex virusSerology (IgG and IgM)
Parvovirus B19PCR
Infection/sepsisBlood culture, urine culture, and chest X-ray
Hepatitis viruses A, B, and CSerology (IgG and IgM)
TyrosinemiaUrinary succinylacetone
GalactosemiaGalactose-1-phosphate uridyltransferase
Hereditary fructose intoleranceTransferrin isoelectric focusing
Niemann-Pick type C diseaseFilipin test
Gaucher diseaseLeukocyte glucocerebrosidase activity
Alpha-1-antitrypsin deficiencyDetection of PiZ allele

PCR = polymerase chain reaction.