Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature

Figure 3

Representative histology. Comparison of core biopsy specimen from the patient’s mediastinal mass with histology of normal thymus. The 2x view demonstrates overall preservation of cortical and medullary regions, with the suggestion of increased RBC’s in the patient sample compared to the normal specimen. This is better seen on the 40x view (arrows) and is consistent with hemorrhage into the thymic tissue. Asterisks mark normal Hassall’s corpuscles, which can be seen in normal tissue and in cases of thymic hyperplasia. Cytokeratin staining in the patient is of normal intensity and distribution, ruling out the differential diagnosis of thymoma.