Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Pediatrics
Volume 2017, Article ID 8397826, 2 pages
Case Report

Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case

1Department of Pediatric Sciences, University of Messina, Messina, Italy
2Department of Pediatric Surgery, University of Messina, Messina, Italy

Correspondence should be addressed to Tommaso Alterio; moc.liamg@oiretla.t

Received 23 July 2016; Accepted 24 November 2016; Published 1 January 2017

Academic Editor: Nina L. Shapiro

Copyright © 2017 Tommaso Alterio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report a case of a 3-year-old North African child, initially assessed for nonspecific urinary symptoms such as haematuria and burning urination. The ultrasound evaluation showed a vegetating mass occupying the lumen with weak vascular signs at the Colour-Doppler evaluation. An explorative cystoscopy was performed and it revealed a nonbleeding lesion, white in colour, pedunculated, projecting into the lumen, and associated with a brown satellite formation. Histological examination showed a mixed Botryoid and Spindle Cell Rhabdomyosarcoma. This mixed histology has not been described before and no statistical data are reported in literature so far. Despite the Embryonal Rhabdomyosarcoma variant being the most common, the association characterized by two histological Rhabdomyosarcoma subtypes such as Botryoid and Spindle Cell is rarely observed and it is important to get an accurate histological diagnosis in order to immediately start the correct treatment protocol.