Case Series

Alveolar Echinococcosis in Children

Table 1

Previously published cases of AE in children.

Author, year of publicationNo. of casesGenderAge (years)Disease presentationTreatmentOutcome

Sailer et al., 1997 [7]1F6Immunocompromised (HIV)
failure to thrive, hepatomegaly, generalized lymphadenopathy, 10 cm intrahepatic mass in the right lobe + smaller masses in the left lobe
ABZ 15 mg/kg/day intermittentlyProgression—new intrahepatic lesion, later unknown

Kinčekova et al., 2008 [8]1F14Headache, fatigue, cough, fever, hepatomegaly, 12.5 × 12.3 cm lesion in the right lobe of the liver with numerous calcificationsABZ 10 mg/kg/day and partial hepatectomyProgress after 1 year of ABZ alone, negative IgG at 3 months after surgery

Honda et al., 2009 [9]1F9Fever, general fatigue, nausea, 5.0 × 6.0 cm multilobular mass + masses between diaphragm and right lobe of the liverPartial hepatectomy + diaphragm and abdominal wall resection ABZ 160 mg/day since surgeryAlive, no signs of recurrence during 15 months of follow-up

Yoshida et al., 2010 [10]96 F
3 M
7 to 152 had abdominal pain and hepatomegaly, 1 had liver dysfunction, and 6 were asymptomatic, diagnosed during mass screeningPartial hepatectomy in 8 patients1 patient died of liver failure (lesions were unresectable), 1 had reresection after 4 years and 7 patients survived up to 33 years without recurrence

Oral et al., 2012 [5]1F12Jaundice, weight loss, abdominal distension, 13 cm mass in the liverABZ 10 mg/kg/day + LTAlive

Nahorski et al., 2013 [11]4N/A6–11N/AABZ in 3 patients ABZ + hepatectomy in 1 patientN/A

Kantarci et al., 2014 [12]1M15Epilepsy and headaches, 18 × 11 cm lesion in the left and partially right lobe of the liver, invading the portal vein and inferior vena cava + left frontotemporal mass and cavitary lesion in the right lungLife-long treatment with ABZ 10 mg/kg/dayN/A

Mack et al., 2019 [13]1M12Left flank pain, extensive lesion from S5/6 to S8 with stenosis of portal veinABZ 8 mg/kg/dayLesion decreased

10th case described in the paper of Honda et al., 2009 [9]; N/A—not available.