Acute Megakaryoblastic Leukemia with Trisomy 21 and Tetrasomy 21 Clones in a Phenotypically Normal Child with Mosaic Trisomy 21

Figure 1

(a) Hypercellular bone marrow core biopsy with lymphocytic infiltrate (arrows) and a few dysplastic cells (hematoxylin-eosin). (b) Reticulin stain demonstrates increased reticulin fibers (arrows). (c) Immunohistochemical staining for CD61 reveals numerous CD61-positive immature cells with megakaryocytic differentiation (arrows).

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