Acute Megakaryoblastic Leukemia with Trisomy 21 and Tetrasomy 21 Clones in a Phenotypically Normal Child with Mosaic Trisomy 21

Table 1

Comparison of modified therapy for child with mosaic T21 with AML16 (NCT03164057) for non-DS-AML and AAML0431 (NCT00369317) for DS-AML.

	AML16 for non-DS-AML	Modified AMKL therapy for child with mosaic T21	AAML0431 for DS-AML
Cytarabine gm/m^2	54	28.6	27.8
Daunorubicin equivalent mg/m^2	414	310	240
Etoposide mg/m^2	1250	1250	750
Total number of cycles	5	6	6