Sclerema Neonatorum in a Term Infant: A Case Report and Literature Review

Table 1

Treatment and outcomes of sclerema neonatorum over the last 25 years.

No	Author(s) and year	Number of patients	Gestation	Management	Outcome
1	Sadana et al., 1997	20		Exchange transfusion with fresh blood^a	50% mortality
2	Battin et al., 2002	1	Term	Conservative	Survived
3	Zeb et al., 2009	51	Preterm	Emollients^a	98% mortality
4	Buster et al., 2013	1	Term	IVIG^a	Died
5	Park and Kim, 2017	1	Term	Conservative, moisturizer	Survived; mild improvement by 12 months
6	Spohn et al., 2016	1	Preterm	Conservative^a	Died
7	Shrestha et al., 2017	1	Preterm	Intravenous steroids^a	Survived
8	Loberger et al., 2019	1	Term	Conservative^a	Survived
9	Younes et al., 2019	1	Preterm	Steroids^a	Not documented

^aAntibiotics given to neonates with sepsis. IVIG, intravenous immunoglobin.