Case Report

Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with 2019 Novel Coronavirus (SARS-CoV-2) Infection

Table 1

Clinical characteristics of patients.

Patient 1Patient 2Patient 3

Patient characteristics
Age (years)1069
SexFemaleFemaleMale
RaceWhite HispanicWhite HispanicAfrican American
Time to presentation4 days4 days4 days
SARS-CoV-2 testing (RT-PCR)PositiveNegative RT-PCR; positive SARS-CoV-2 IgGPositive
Laboratory values
Leucocytes (K/μL) (4.5–13.5)16.14.720.3
Platelets (K/μL) (140–440)25286243
Neutrophils (K/μL) (1.30–9)13.684.4216.04
Lymphocytes (K/μL) (1.90–7.5)1.450.092.23
C-reactive protein (mg/L) (<9.9)202.4213284.4
Erythrocyte sedimentation rate (mm/hour) (0–20)465650
Fibrinogen (mg/dL) (183–503)640501495
D-dimers (mcg/mL) (≤0.5)2.9817.824.29
Ferritin (ng/ml) (13–145)2034902574
Albumin (g/dL) (3.8–5.4)3.02.53.4
Creatinine (mg/dL) (0.6 to 1.3)0.560.622.08
Troponin (ng/mL) (0.00–0.030)0.5390.2741.456
B-type natriuretic peptide (pg/mL) (1–100)3961213383
Chest imagingNot doneChest CT scan: bilateral infiltrates with small pleural effusionChest radiograph: Bilateral infiltrates
Transthoracic echocardiographic findingsHyperdynamic left ventricular systolic function; shortening fraction of 43.7%Hyperdynamic left ventricular systolic function; shortening fraction of 40%Borderline low systolic function with a shortening fraction of 29–30%. No coronary artery ectasia or aneurysms. No evidence of pulmonary hypertension. Trivial pericardial effusion.
Electrocardiography (EKG): nonspecific T-wave changes and low-voltage QRS.
Duration of ICU stay (days)4126