Case Report

Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler

Table 1

Pertinent laboratory data on admission.

HematologyAdmission values (reference range)Outpatient values (reference range)

 White blood cells (K/μL)8.1 (6–17.5)11.68
 Hemoglobin (g/dL)5.1 (10.5–13.5)11.3
 Platelets (K/μL)51 (150–350)450
 Reticulocyte (%)8.4% (0–2.5%)1.2
 Peripheral smearSchistocytes
 CoombsNegative
Coagulation
 D-dimer (ng/mL)4098 (<500)
 Haptoglobin (mg/dL)<8 (30–250)134
 Lactate dehydrogenase (U/L)833 (100–260)300
 PT10.4 (9.9–13.4 sec)
 aPTT29.4 (24.0–39.2 sec)
Urine
 ColorAmberYellow
 Specific gravity1.020 (1.005–1.030)1.025
 Protein3+Trace
 Blood3+Negative
 Microscopic (/hpf)8 RBC (0–4/hpf), 21 WBC (0–5/hpf)5 RBC, 2 WBC
 Protein/creatine ratio (g/mmol)5.1 (<0.2)0.25
Inflammatory and cardiovascular parameters
 Ferritin (ng/mL)447 (16–300)207
 ESR (mm/h)25 (0–20)
 Interleukin-6 (pg/mL)3.0 (≤1.8)
 NT-pro BNP (pg/mL)3685 (<125)
Chemistry
 Serum creatine (mg/dL)0.71 (0.2–0.4)0.32
 eGFR (ml/min/1.73 m2)67 (89–165)127
 BUN (mg/dL)47 (5–18)10
 AST (U/L)62 (10–40)45
 C3 (mg/dL)106 (50–180)
 Albumin (g/dL)3.4 (3.2–4.7 g/dL)3.9
 ANANegative
 ADAMSTS13 (%)>100