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Case Reports in Psychiatry
Volume 2012, Article ID 946109, 4 pages
Case Report

Autism in Early Childhood: An Unusual Developmental Course—Three Case Reports

The Hannah Khoushy Child Development Center, Bnai Zion Medical Center and The Rappaport Family Faculty of Medicine, The Technion-Israel Institute of Technology, P.O. Box 4940, 25148 Haifa, Israel

Received 14 February 2012; Accepted 10 April 2012

Academic Editors: F. Oyebode, S. Shimodera, and M. Thompson

Copyright © 2012 Michal Cohen-Ophir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Autistic spectrum disorder (ASD) is typically characterized by either an emerging and gradual course or developmental regression in early childhood. The versatile clinical course is progressively acknowledged in recent years. Children with developmental disorders in general are referred to the Child Development Center for a multidisciplinary assessment, investigation, treatment and followup. We report three infants with an initial diagnosis of developmental delays, recovery of normal development following intervention in a multidisciplinary center, and subsequent regression into classic autism following their discharge from the program. An extensive medical workup was noncontributory. This unusual presentation, to our knowledge not reported previously, should be recognized by professionals involved in child development and psychiatry.