Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Psychiatry
Volume 2015, Article ID 456830, 4 pages
http://dx.doi.org/10.1155/2015/456830
Case Report

Is Valproate Depressogenic in Patients Remitting from Acute Mania? Case Series

1Departments of Psychiatry and Medicine, Schulich School of Medicine and Dentistry, Western University, Victoria Hospital, London Health Sciences Centre, A2-513, London, ON, Canada N6A 5W9
2Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, Victoria Hospital, London Health Sciences Centre, B-8, London, ON, Canada N6A 5W9

Received 23 August 2015; Accepted 3 November 2015

Academic Editor: Liliana Dell’Osso

Copyright © 2015 Kamini Vasudev and Priya Sharma. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. N. Yatham, S. H. Kennedy, S. V. Parikh et al., “Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013,” Bipolar Disorders, vol. 15, no. 1, pp. 1–44, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. American Psychiatric Association, “Practice guideline for the treatment of patients with bipolar disorder (revision),” The American Journal of Psychiatry, vol. 159, no. 4, supplement, pp. 1–50, 2002. View at Google Scholar
  3. G. M. Goodwin, “Evidence-based guidelines for treating bipolar disorder: revised second edition—recommendations from the British Association for Psychopharmacology,” Journal of Psychopharmacology, vol. 23, no. 4, pp. 346–388, 2009. View at Publisher · View at Google Scholar
  4. K. A. Macritchie, J. R. Geddes, J. Scott, D. R. Haslam, M. Silva de Lima, and G. Goodwin, “Valproate for acute mood episodes in bipolar disorder,” Cochrane Database of Systematic Reviews, vol. 1, Article ID CD004052, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. D. J. Bond, R. W. Lam, and L. N. Yatham, “Divalproex sodium versus placebo in the treatment of acute bipolar depression: a systematic review and meta-analysis,” Journal of Affective Disorders, vol. 124, no. 3, pp. 228–234, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. L. A. Smith, V. R. Cornelius, J. M. Azorin et al., “Valproate for the treatment of acute bipolar depression: systematic review and meta-analysis,” Journal of Affective Disorders, vol. 122, no. 1-2, pp. 1–9, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Cipriani, K. Reid, A. H. Young, K. Macritchie, and J. Geddes, “Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder,” Cochrane Database of Systematic Review, vol. 10, Article ID CD003196, 2013. View at Google Scholar · View at Scopus
  8. C. L. Bowden, J. R. Calabrese, S. L. McElroy et al., “A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder,” Archives of General Psychiatry, vol. 57, no. 5, pp. 481–489, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. The BALANCE Investigators and Collaborators, “Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial,” The Lancet, vol. 375, no. 9712, pp. 385–395, 2010. View at Publisher · View at Google Scholar
  10. J. R. Calabrese, M. D. Shelton, D. J. Rapport et al., “A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorder,” The American Journal of Psychiatry, vol. 162, no. 11, pp. 2152–2161, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. S. L. McElroy, P. E. Keck Jr., S. P. Stanton, K. C. Tugrul, J. A. Bennett, and S. M. Strakowski, “A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania,” Journal of Clinical Psychiatry, vol. 57, no. 4, pp. 142–146, 1996. View at Google Scholar · View at Scopus
  12. R. M. Hirschfeld, M. H. Allen, J. P. McEvoy, P. E. Keck Jr., and J. M. Russell, “Safety and tolerability of oral loading divalproex sodium in acutely manic bipolar patients,” The Journal of Clinical Psychiatry, vol. 60, no. 12, pp. 815–818, 1999. View at Publisher · View at Google Scholar · View at Scopus
  13. C. L. Bowden, A. C. Swann, J. R. Calabrese et al., “A randomized, placebo-controlled, multicenter study of divalproex sodium extended release in the treatment of acute mania,” Journal of Clinical Psychiatry, vol. 67, no. 10, pp. 1501–1510, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. K. Vasudev, U. Goswami, and K. Kohli, “Carbamazepine and valproate monotherapy: feasibility, relative safety and efficacy, and therapeutic drug monitoring in manic disorder,” Psychopharmacology, vol. 150, no. 1, pp. 15–23, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. M. H. Allen, R. M. Hirschfeld, P. J. Wozniak, J. D. Baker, and C. L. Bowden, “Linear relationship of valproate serum concentration to response and optimal serum levels for acute mania,” American Journal of Psychiatry, vol. 163, no. 2, pp. 272–275, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Machino, H. Jitsuiki, Y. Okamoto et al., “The valproate serum level in maintenance therapy for bipolar disorder in Japan,” Hiroshima Journal of Medical Sciences, vol. 62, no. 1, pp. 7–12, 2013. View at Google Scholar · View at Scopus