Case Reports in Psychiatry / 2015 / Article / Tab 1

Case Report

Three Patients Needing High Doses of Valproic Acid to Get Therapeutic Concentrations

Table 1

Explaining VPA C/D ratio use with VPA concentrations from a published case [29].

FormulationVPA dose (mg/day)Concentration (g/mL)C/D ratioC/D ratio × 1000

ECDVNa10001120.112112
ECDVNa750870.116116
ECDVNa500660.132132
ECDVNa500640.128128

C/D: concentration-to-dose; ECDVNa: divalproex sodium enterocoated; VPA: valproic acid.

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