Case Report

A Case of Neuroleptic Malignant Syndrome in a Profoundly Intellectually Disabled Patient with Successful Reintroduction of Antipsychotic Therapy with Quetiapine

Table 1

Tetrad or cardinal features of NMS [6ā€“10].

Typical SymptomsPrevalence in NMS

Acute Mental Status Changes82%
Severe Muscle Rigidity45-92%
Hyperthermia87% (38C), 40% (40C)
Autonomic Instability88% (tachycardia), 61-77% (labile or high BP), 73% (Tachypnea)