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Case Reports in Psychiatry
Volume 2018, Article ID 9839252, 3 pages
Case Report

Treatment of Acute Psychosis with Second-Generation Antipsychotics in a Patient with Left Temporal Lobe Lesion

Department of Psychiatry, Naval Medical Center Portsmouth, Portsmouth, VA, USA

Correspondence should be addressed to Richard Shehane; moc.liamg@enahehsr

Received 27 September 2017; Accepted 3 January 2018; Published 5 February 2018

Academic Editor: Erik Jönsson

Copyright © 2018 Richard Shehane et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present a case of rapid onset severe psychosis followed by suicide attempt in a United States Navy sailor. Investigation revealed a left temporal lobe brain mass suspicious for low-grade glioma. After hospitalization and medical management with olanzapine and lurasidone the patient’s psychosis improved. The purpose of this paper is to add to the existing case reports that suggest a relationship between temporal lobe lesions and psychiatric illness, specifically psychosis. In addition, this case adds insight into the effectiveness of medical therapy for brain tumor patients that are not immediate candidates for neurosurgical intervention.