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Case Reports in Pulmonology
Volume 2013, Article ID 341872, 3 pages
Case Report

Metastatic Pulmonary Calcification in Multiple Myeloma in a 45-Year-Old Man

1Department of Medicine, Texas A&M University, 7613 Lake Bolsena, Corpus Christi, TX 78413, USA
2Pulmonary Associates of Corpus Christi, 1177 Wheeler Avenue, Aransas Pass, TX 78366, USA
3Department of Acute and Continuing Care, The University of Texas Health Science Center, Houston TX 77030, USA

Received 24 February 2013; Accepted 27 March 2013

Academic Editors: E. Fernández Pérez, G. Hillerdal, K. M. Nugent, M. Takao, and K. Watanabe

Copyright © 2013 Salim R. Surani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Metastatic calcification has been associated with multiple-myeloma-induced hypercalcemia. Despite of a relatively high prevalence of metastatic pulmonary calcification in patients with multiple myeloma, only a few cases have been clinically and radiologically detected. A 45-year-old Hispanic male presented to the Emergency Department with complaint of worsening weakness and myalgia. Laboratory findings revealed renal insufficiency and hypercalcemia. CT scan of chest revealed calcified pleural and pulmonary nodule. Technetium (Tc) 99 bone scan revealed diffuse activity in the pulmonary parenchyma consistent with metastatic pulmonary calcification. Metastatic pulmonary calcification, despite its high prevalence, remains undetected. This is, in part, due to its radiographic characteristic properties that evade detection by routine imaging studies. We present a case of a metastatic pulmonary calcification in a patient diagnosed with multiple myeloma and chronic kidney disease, as well as a brief literature review including clinical findings and treatment options.