Case Report

Pulmonary Neuroendocrine Cell Hyperplasia Associated with Surfactant Protein C Gene Mutation

Figure 3

(a) Hematoxylin and eosin (H&E) stain 4x showed chronic interstitial pneumonia, overall pattern most consistently with NSIP. (b) H&E stain 10x showed alveolar septal thickening. (c) Synaptophysin 4x showed PNEC hyperplasia. (d) Synaptophysin 10x showed a carcinoid tumorlet sized approximately 2.5–3 mm.
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