Case Reports in Pulmonology / 2020 / Article / Tab 2

Case Report

Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Literature Review

Table 2

Summary of cases presenting cosecretion of PTHrP and calcitriol in solid tumors.

AuthorAgeSexPrimary tumorHistological typeTx of HCMSxCTxRTxCourse of the tumorOutcome of HCMEffective Tx of HCM

Hoekman et al. [2]70FOvarian carcinomaAdenocarcinomaPamidronateYesNoNoResectionImprovementOperation
Van den Eynden et al. [3]59MPancreatic neuroendocrine tumorNeuroendocrine tumorPamidronateYesYesNoReductionImprovementChemotherapy
Zoledronic acid
Shivnani et al. [4]57MRenal cell carcinomaClear cellPamidronateNoYesNoProgressionImprovementPrednisolone
Rodriguez-Gutierrez et al. [5]35MSeminomaSeminomaCalcitoninNoYesNoReductionImprovementChemotherapy
Nemr et al. [6]60MLung cancerSquamousCalcitoninNoNoNoProgressionNo improvementNone
Zoledronic acid
Ogawaa71MLung cancerSquamousPrednisoloneNoYesNoProgressionImprovementPrednisolone

CTx: chemotherapy; HCM: hypercalcemia of malignancy; RTx: radiation therapy; Sx: surgery; Tx: treatment. aPresent case.

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