A Complete Constellation of Nervous System Lesions of NF2: Imaging Evaluation

Table 1

Gutmann et al. [1].

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Definite diagnoses of NF2

(i) bilateral CN VIII schwannomas on MRI or CT scan (no biopsy necessary)

(ii) First-degree relative with NF2 and either unilateral early-onset CNVIII schwannoma (age <30 y) or any two of the following:

  (1) meningioma

  (2) glioma

  (3) schwannoma

  (4) juvenile posterior subcapsular lenticular opacity (juvenile cortical cataract)

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Presumptive diagnoses of NF2

(i) Early onset of unilateral CN VIII schwannomas on MRI or CT scan detected in patients younger than 30 years and one of the following:

  (1) meningioma

  (2) glioma

  (3) schwannoma

  (4) juvenile posterior subcapsular lenticular opacity

(ii) Multiple meningiomas (>2) and unilateral CN VIII schwannoma or one of the following:

  (1) glioma

  (2) schwannoma

  (3) juvenile posterior subcapsular lenticular opacity

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