Case Report

Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis

Figure 1

T2w FLAIR images (Philips Achieva 3T, TR = 9000 ms; TE = 123 ms; inversion time TI = 2500 ms; FA 180). Juxtaventricular peri- and paratrigonal white matter lesion underneath the frontal lobe of the left hemisphere (arrows) in a 44-year-old man with a 12-year history of MS and affected by natalizumab-related PML in the coronal (a), (b) and axial plan (c), (d). Lesion reduction between December 2011 (a), (c) and May 2012 (b), (d). A bilateral white matter periventricular lesion load related to MS is also seen (arrow heads).
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(a)
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(b)
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(c)
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(d)