Reversed Halo Sign in Tuberous Sclerosis Complex

Figure 2

Microscopic findings. (a) Enlarged cuboidal cells have abundant, eosinophilic cytoplasm and large, round nuclei lining mildly thickened alveolar septa (hematoxylin and eosin stain). (b) Alveolar septa are focally composed of thickened elastic fibers (Elastica-Masson trichrome stain). (c) Enlarged cuboidal cells are positive for phospho-S6 ribosomal protein.

(a)

(b)

(c)