Magnetic Resonance Imaging in Marchiafava-Bignami Syndrome: A Cornerstone in Diagnosis and Prognosis

Table 2

Correlation of imaging findings in MBS with pathophysiology [1, 6].

	MRI findings	Underlying pathophysiology
1	Hyperintensity on T2 weighted images	Edema and myelin damage
2	Hypointensity on T1 weighted images	Total loss of myelin with replacement of the region by a cyst
3	Hyperintense rims and hypointense cores on FLAIR images	Damage to the myelin at the rim with a central necrotic area
4	Uniformly hyperintense lesions on FLAIR	Mixture of demyelination and edema
5	Areas of restricted diffusion on DWI (acute phase)	Cytotoxic edema