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Case Reports in Radiology
Volume 2014, Article ID 724671, 4 pages
Case Report

Antenatal Diagnosis of Alobar Holoprosencephaly

Department of Radiodiagnosis, JSS Medical College, Mysore, Karnataka 570004, India

Received 21 February 2014; Accepted 23 June 2014; Published 14 July 2014

Academic Editor: Alberto Spalice

Copyright © 2014 Rajesh Raman and Geetha Mukunda Jagadesh. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A twenty-year-old second gravida presented to the department of radiodiagnosis for routine obstetric ultrasound examination. Ultrasonography revealed a live fetus of 17 weeks with absent falx, fused thalami, monoventricle, proboscis, and cyclopia. Fetal MRI was performed and the findings were confirmed. Even though ultrasonography is diagnostic in the detection of fetal anomalies, MRI plays a vital role due to its multiplanar capability and excellent soft tissue resolution. The importance of presenting this classical case of alobar holoprosencephaly is to sensitize the clinicians and radiologists to the imaging manifestations of holoprosencephaly and to stress the importance of early diagnosis. If diagnosed in utero at an early stage of pregnancy, termination can be performed and maternal psychological trauma of bearing a deformed fetus can be avoided.