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Case Reports in Radiology
Volume 2015, Article ID 268974, 5 pages
Case Report

Rapid Pituitary Apoplexy Regression: What Is the Time Course of Clot Resolution?

1College of Medicine, Howard University, Washington, DC 20059, USA
2Department of Neurological Surgery, Mayo Clinic, Rochester, MN 55905, USA

Received 11 December 2014; Revised 2 March 2015; Accepted 2 March 2015

Academic Editor: Ruben Dammers

Copyright © 2015 Devon L. Jackson and Jamie J. Van Gompel. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 29-year-old male patient with a functioning pituitary macroadenoma is discussed. The pituitary mass was detected by MRI after the patient presented with sudden onset of headache, suggestive of an apoplectic event. The headache resolved with analgesic medications. Within a follow-up period of one week, the pituitary mass had spontaneously regressed to nearly half its original size without any therapy. The patient never reported any visual complaints and displayed no signs of hypopituitarism. Elevated prolactin levels were present. Seven weeks after the initial event, the pituitary mass showed continued regression on MRI. Prolactin levels remained elevated. This case provides a unique look at the rapid spontaneous regression of mass effect that may occur following apoplexy of a pituitary adenoma.