A Case Series of Breast Metastases from Different Extramammary Malignancies and Their Literature Review

Figure 7

Case 7. A 71-year-old woman with malignant melanoma. Two years after diagnosis, the patient presented with a palpable mass in the left breast. Mammogram showed many oval masses with circumscribed margins (a–b). These findings were corroborated on ultrasound, exhibiting oval masses with indistinct and microlobulated margins and a heterogeneous echo pattern (c–f). Edema was also evident (e–f). Metastatic melanoma to the breast was confirmed following a histopathological analysis of the breast specimen. HE staining and immunohistochemistry analysis of the metastases. HE staining revealed the malignant cells in the breast tumor (g), and the immunohistochemistry analysis indicated that the cells were positive for HMB45 (h).

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