Vertebral Column Metastases from an Esthesioneuroblastoma: Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup

Table 1

Cedars-Sinai classification system for metastatic esthesioneuroblastoma to the spine.

Stage	Anatomic location of lesion
CS0-leptomeningeal disease	Involvement of the CSF and leptomeninges (arachnoid and pia mater)
CS1a-one level disease	Involves one level of the spine or spinal cord: cervical, thoracic, lumbar, or sacral
CS1b-one level disease and leptomeningeal disease	Involves one level of the spine or spinal cord: cervical, thoracic, lumbar, or sacral; with involvement of the CSF and leptomeninges (arachnoid and pia mater)
CS2a-two level disease	Involves two levels of the spine or spinal cord: cervical, thoracic, lumbar, or sacral
CS2b-two level disease and leptomeningeal disease	Involves two levels of the spine or spinal cord: cervical, thoracic, lumbar, or sacral; with involvement of the CSF and leptomeninges (arachnoid and pia mater)
CS3a-three level disease	Involves three levels of the spine or spinal cord: cervical, thoracic, lumbar, or sacral
CS3b-three level disease and leptomeningeal disease	Involves three levels of the spine or spinal cord: cervical, thoracic, lumbar, or sacral; with involvement of the CSF and leptomeninges (arachnoid and pia mater)
CS4a-four level disease	Involves four levels of the spine or spinal cord: cervical, thoracic, lumbar, or sacral
CS4b-four level disease and leptomeningeal disease	Involves four levels of the spine or spinal cord: cervical, thoracic, lumbar, or sacral; with involvement of the CSF and leptomeninges (arachnoid and pia mater)