Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Surgery
Volume 2014, Article ID 581823, 4 pages
Case Report

Adenoid Cystic Carcinoma of the Submandibular Gland, Locoregional Recurrence, and a Solitary Liver Metastasis More Than 30 Years Since Primary Diagnosis

1Department of HPB and Transplant Surgery, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
2Department of Histopathology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK

Received 6 July 2014; Accepted 7 October 2014; Published 27 October 2014

Academic Editor: Francesco Petrella

Copyright © 2014 A. Coupland et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Adenoid cystic carcinoma (ACC) is a relatively rare tumour of the salivary glands, accounting for approximately 5%–10% of all salivary gland tumours. An important feature of ACCs is the long clinical course with a high rate of distant metastases. The preferential sites of metastases are the lung and bone, followed by the brain and liver. Most liver metastases are derived from nonparotid ACCs, and the presentation is often related to local recurrence or metastases to other organs. Solitary metastases to the liver are rare and optimal management is unknown. We present the case of a metastatic ACC to the liver with primary disease presentation at a young age. We discuss our management and other potential treatment modalities.