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Case Reports in Surgery
Volume 2014, Article ID 643746, 5 pages
Case Report

A Case of Retroperitoneal Castleman’s Disease and an Update on the Latest Evidence

2nd Propedeutic Department of Surgery, University of Athens Medical School, General Hospital “Laikon”, Agiou Thoma 15b, Vasilissis Sofias 49, Kolonaki, 106 76 Athens, Greece

Received 4 June 2014; Revised 2 September 2014; Accepted 13 October 2014; Published 5 November 2014

Academic Editor: Gregorio Santori

Copyright © 2014 Eleftherios Spartalis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Castleman’s disease is a benign lymphoproliferative condition with three distinct histological subtypes. Clinically it presents in either a unicentric or multicentric manner and can affect various anatomic regions, the mediastinum being the most frequent location. We herein present a rare case of unifocal retroperitoneal mass proved to be hyaline vascular Castleman’s disease. We perform a review of the current literature pertaining to such lesions, focusing on the management of the various clinical and histological variants of the disease. Surgical excision is the treatment of choice for unifocal Castleman’s disease.