Pediatric Granular Cell Tumor of the Breast: A Case Report and Review of the Literature

Figure 2

(a) Margin of tumor, cords and files of tumor cells in compressed collagenous stroma, with normal ducts, minimal inflammatory reaction (H&E). (b) Center of the tumor; granularity of the abundant eosinophilic cytoplasm is apparent (H&E). (c) Low power architecture of tumor, with swirling cords; peripherally entrapped normal duct (middle of picture); compressed, minimally infiltrative strands on the right, along with normal breast lobules Immunostain for S100. (d) Center of the tumor, positive for S100 immunohistochemical stain. (e) Margin of the tumor (Immunostain for S100); short infiltrative tumor strands (right lower quadrant of image) in compressed stroma (right upper quadrant), entrapping normal ducts (left lower corner) by the tumor margin (left upper quadrant). (f) Diffuse immunohistochemical staining of the tumor with CD68.

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