Inflammatory Myofibroblastic Tumor of the Breast

Figure 4

(a) Hematoxylin-eosin (H&E) staining of the lesion (magnification ×10): significant inflammatory invasion by lymphocytes and plasma cells; presence of stacks of fusiform myofibroblasts and few gigantic cells. (b) Vimentin staining of the lesion (magnification ×10): presence of myofibroblasts and lymphocytes. (c) Actin staining of the lesion (magnification ×40): presence of myofibroblasts which stain positive for actin. (d) Keratin 34BE12 staining (magnification ×10): myofibroblasts immunonegative to keratin 34BE12. (e) CD20 staining (magnification ×4): CD20 positive B-lymphocytes. (f) CD3 staining (magnification ×4): CD3 positive T-lymphocytes.

(a)

(b)

(c)

(d)

(e)

(f)