Multiple Gastric Gastrointestinal Stromal Tumors in a Patient with Neurofibromatosis Type 1

Table 1

Cases of gastric GISTs in patients with NF 1.

Case number	Age	Sex	Total number of GISTs	Site	Number of GISTs	Size (cm)	Genetic analysis		Reference number
							c-kit	PDGFRA
1	32	F	4	Stomach	ND	2–10	NE	NE	[7]
				Jejunum	ND
2	82	F	Numerous	Stomach	ND	0.5–2.5	WT	WT	[7]
				Small intestine	ND
				Colon	ND
3	77	M	5	Stomach	ND	0.3–2.0	WT	WT	[7]
				Esophagus	ND
				Jejunum	ND
				Ileum	ND
4	64	M	>100	Stomach	ND	0.1–3.5	WT	WT	[7]
				Small intestine	ND
				Colon	ND
5	58	M	5	Stomach	2	0.3, 3.0	WT	WT	[8]
				ND	3	ND
6	64	F	Multiple	Stomach	1	11	WT	WT	[9]
				Small intestine	Multiple	Maximum 3.5
7	40	F	1	Stomach	1	2.5	WT	WT	[10]
8	67	M	1	Stomach	1	Voluminous	NE	NE	[11]
9	71	M	1	Stomach	1	3.6	NE	NE	[3]
10	38	F	1	Stomach	1	8	NE	NE	[12]
11	59	F	4	Stomach	2	0.2, 0.5	WT	WT	[1]
				Jejunum	2	0.8, 3.0

ND: not described, NE: not examined, and WT: wild type.