Table 1: Fletcher et al. prognostic classification.

Size (largest dimension)Mitotic count

Very low risk<2 cm<5/50 HPF
Low risk2–5 cm<5/50 HPF
Intermediate risk<5 cm6–10/50 HPF
5–10 cm<5/50 HPF
High risk>5 cm>5/50 HPF
>10 cmAny mitotic rate