Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Surgery
Volume 2017, Article ID 3074240, 8 pages
https://doi.org/10.1155/2017/3074240
Case Report

Pediatric Ovarian Growing Teratoma Syndrome

1Department of Surgery, Children’s Mercy Hospital, Kansas City, MO, USA
2Department of Obstetrics and Gynecology, University of Missouri, Kansas City, Kansas City, MO, USA
3Department of Pathology, Children’s Mercy Hospital, Kansas City, MO, USA
4Department of Hematology, Oncology, and Bone Marrow Transplantation, Children’s Mercy Hospital, Kansas City, MO, USA

Correspondence should be addressed to Rebecca M. Rentea; ude.hmc@aetnerr

Received 6 December 2016; Revised 3 April 2017; Accepted 3 May 2017; Published 1 June 2017

Academic Editor: Menelaos Zafrakas

Copyright © 2017 Rebecca M. Rentea et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. Gorbatiy, P. Spiess, and L. Pisters, “The growing teratoma syndrome: current review of the literature,” Indian Journal of Urology, vol. 25, no. 2, pp. 186–189, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. L. Zagamé, P. Pautier, P. Duvillard, D. Castaigne, C. Patte, and C. Lhommé, “Growing teratoma syndrome after ovarian germ cell tumors,” Obstetrics and Gynecology, vol. 108, no. 3 I, pp. 509–514, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. C.-H. Lai, T.-C. Chang, S. Hsueh et al., “Outcome and prognostic factors in ovarian germ cell malignancies,” Gynecologic Oncology, vol. 96, no. 3, pp. 784–791, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. F. André, K. Fizazi, S. Culine et al., “The growing teratoma syndrome: results of therapy and long-term follow-up of 33 patients,” European Journal of Cancer, vol. 36, no. 11, pp. 1389–1394, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Merard, R. Ganesan, and L. Hirschowitz, “Growing teratoma syndrome: A report of 2 cases and review of the literature,” International Journal of Gynecological Pathology, vol. 34, no. 5, pp. 465–472, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. H. Amsalem, M. Nadjari, D. Prus, N. Hiller, and A. Benshushan, “Growing teratoma syndrome vs. chemotherapeutic retroconversion: Case report and review of the literature,” Gynecologic Oncology, vol. 92, no. 1, pp. 357–360, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. H. I. Yakut, E. Korkmaz, N. Cetinkaya, E. Baser, C. Irkkan, and T. Gungor, “Recurrent ‘growing teratoma syndrome’ in an adolescent girl with a history of ovarian immature teratoma: A case report*,” Journal of Obstetrics and Gynaecology, vol. 36, no. 7, pp. 845–847, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. L. E. Weinberg, J. R. Lurain, D. K. Singh, and J. C. Schink, “Survival and reproductive outcomes in women treated for malignant ovarian germ cell tumors,” Gynecologic Oncology, vol. 121, no. 2, pp. 285–289, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. R. N. Eskander, R. E. Bristow, N. C. Saenz et al., “A retrospective review of the effect of surgeon specialty on the management of 190 benign and malignant pediatric and adolescent adnexal masses,” Journal of Pediatric and Adolescent Gynecology, vol. 24, no. 5, pp. 282–285, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Pashankar, J. P. Hale, H. Dang et al., “Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative,” Cancer, vol. 122, no. 2, pp. 230–237, 2016. View at Publisher · View at Google Scholar · View at Scopus
  11. U. Göbel, G. Caluininus, M. Blohm et al., “Extracranial non-testicular teratoma in childhood and adolescence: introduction of a risk score for stratification of therapy,” Klinische Padiatrie, vol. 209, no. 4, pp. 228–234, 1997. View at Publisher · View at Google Scholar · View at Scopus
  12. P. J. DiSia, A. Saltz, and A. R. Kagan, “Chemotherapeutic retroconversion of immature teratoma of the ovary,” Obstetrics and Gynecology, vol. 49, pp. 1346–1350, 1997. View at Google Scholar
  13. C. J. Logothetis, M. L. Samuels, A. Trindade, and D. E. Johnson, “The growing teratoma syndrome,” Cancer, vol. 50, no. 8, pp. 1629–1635, 1982. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Soufi, R. M. Lupinacci, G. Godiris-Petit et al., “Growing teratoma syndrome of the ovary presenting with liver metastasis: report of a case,” European Journal of Gynaecological Oncology, vol. 36, no. 4, pp. 473–476, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Li, Z. Liu, C. Dong et al., “Growing Teratoma Syndrome Secondary to Ovarian Giant Immature Teratoma in an Adolescent Girl: A Case Report and Literature Review,” Medicine, vol. 95, no. 7, p. e2647, 2016. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Shigeta, E. Kobayashi, K. Sawada et al., “Laparoscopic excisional surgery for growing teratoma syndrome of the ovary: Case report and literature review,” Journal of Minimally Invasive Gynecology, vol. 22, no. 4, pp. 668–674, 2015. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Oya, A. Saito, A. Okano, E. Arai, K. Yanai, and T. Matsui, “The pathogenesis of intracranial growing teratoma syndrome: Proliferation of tumor cells or formation of multiple expanding cysts? Two case reports and review of the literature,” Child's Nervous System, vol. 30, no. 8, pp. 1455–1461, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. K. Shibata, H. Kajiyama, and F. Kikkawa, “Growing teratoma syndrome of the ovary showing three patterns of metastasis: A case report,” Case Reports in Oncology, vol. 6, no. 3, pp. 544–549, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. D. J. Lee, H. Djaladat, N. N. Tadros et al., “Growing teratoma syndrome: clinical and radiographic characteristics,” International Journal of Urology, 2014. View at Publisher · View at Google Scholar
  20. P. E. Spiess, W. Kassouf, G. A. Brown et al., “Surgical management of growing teratoma syndrome: the M. D. Anderson Cancer Center Experience,” Journal of Urology, vol. 177, no. 4, pp. 1330–1334, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Kikawa, Y. Todo, S. Minobe, K. Yamashiro, H. Kato, and N. Sakuragi, “Growing teratoma syndrome of the Ovary: A case report with FDG -PET findings,” Journal of Obstetrics and Gynaecology Research, vol. 37, no. 7, pp. 926–932, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. B. Djordjevic, E. D. Euscher, and A. Malpica, “Growing teratoma syndrome of the ovary: Review of literature and first report of a carcinoid tumor arising in a growing teratoma of the ovary,” American Journal of Surgical Pathology, vol. 31, no. 12, pp. 1913–1918, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Scavuzzo, Z. A. Santana Ríos, and N. R. Noverón, “Growing Teratoma Syndrome,” Case Reports in Urology, vol. 2014, article 139425, 2014. View at Publisher · View at Google Scholar
  24. M. Stella, A. Gandini, P. Meeus et al., “Retroperitoneal vascular surgery for the treatment of giant growing teratoma syndrome,” Urology, vol. 79, no. 2, pp. 365–370, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. A. D. Ahlgren, C. R. Simrell, T. J. Triche, R. Ozols, and S. H. Barsky, “Sarcoma arising in a residual testicular teratoma after cytoreductive chemotherapy,” Cancer, vol. 54, no. 9, pp. 2015–2018, 1984. View at Publisher · View at Google Scholar · View at Scopus
  26. U. Al-Jumaily, M. Al-Hussaini, F. Ajlouni et al., “Ovarian germ cell tumors with rhabdomyosarcomatous components and later development of growing teratoma syndrome: a case report,” Journal of Medical Case Reports, vol. 6, article 13, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. E. Bentivegna, H. Azaïs, C. Uzan et al., “Surgical Outcomes After Debulking Surgery for Intraabdominal Ovarian Growing Teratoma Syndrome: Analysis of 38 Cases,” Annals of Surgical Oncology, vol. 22, pp. 964–970, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Daher, E. Riachy, A. Khoury, L. Raffoul, C. Ghorra, and C. Rehayem, “Growing teratoma syndrome: First case report in a 4-year-old girl,” Journal of Pediatric and Adolescent Gynecology, vol. 28, no. 1, pp. e5–e7, 2015. View at Publisher · View at Google Scholar · View at Scopus
  29. E. Bentivegna, C. Gonthier, C. Uzan et al., “Gliomatosis peritonei: A particular entity with specific outcomes within the growing teratoma syndrome,” International Journal of Gynecological Cancer, vol. 25, no. 2, pp. 244–249, 2015. View at Publisher · View at Google Scholar · View at Scopus
  30. S. J. Robboy and R. E. Scully, “Ovarian teratoma with glial implants on the peritoneum. An Analysis of 12 Cases,” Human Pathology, vol. 1, no. 4, pp. 643–653, 1970. View at Publisher · View at Google Scholar · View at Scopus
  31. L. D. Truong, S. Jurco III, and M. H. McGavran, “Gliomatosis peritonei. Report of two cases and review of literature,” American Journal of Surgical Pathology, vol. 6, no. 5, pp. 443–449, 1982. View at Publisher · View at Google Scholar · View at Scopus
  32. D. Harms, U. Janig, and U. Gobel, “Gliomatosis peritonei in childhood and adolescence. Clinicopathological study of 13 cases including immunohistochemical findings,” Pathology Research and Practice, vol. 184, no. 4, pp. 422–430, 1989. View at Publisher · View at Google Scholar · View at Scopus
  33. S. N. J. Nielsen, B. W. Scheithauer, and T. A. Gaffey, “Gliomatosis peritonei,” Cancer, vol. 56, no. 10, pp. 2499–2503, 1985. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Gheorghisan-Galateanu, D. C. Terzea, M. Carsote, and C. Poiana, “Immature ovarian teratoma with unusual gliomatosis,” Journal of Ovarian Research, vol. 6, no. 1, article no. 28, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. D. A. Hill, L. P. Dehner, F. V. White, and J. C. Langer, “Gliomatosis peritonei as a complication of a ventriculoperitoneal shunt: Case report and review of the literature,” Journal of Pediatric Surgery, vol. 35, no. 3, pp. 497–499, 2000. View at Publisher · View at Google Scholar · View at Scopus
  36. N. R. Yoon, J.-W. Lee, B.-G. Kim et al., “Gliomatosis peritonei is associated with frequent recurrence, but does not affect overall survival in patients with ovarian immature teratoma,” Virchows Archiv, vol. 461, no. 3, pp. 299–304, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. K. Byrd, M. P. Stany, N. C. Herbold et al., “Growing teratoma syndrome: brief communication and algorithm for management,” The Australian & New Zealand Journal of Obstetrics & Gynaecology, vol. 53, no. 3, pp. 318–321, 2013. View at Publisher · View at Google Scholar · View at Scopus
  38. P. Coscojuela, J. Llauger, C. Pérez, J. Germá, and E. Castañer, “The growing teratoma syndrome: radiologic findings in four cases,” European Journal of Radiology, vol. 12, no. 2, pp. 138–140, 1991. View at Publisher · View at Google Scholar · View at Scopus
  39. E. Moskovic, T. Jobling, C. Fisher, E. Wiltshaw, and C. Parsons, “Retroconversion of immature teratoma of the ovary: CT appearances,” Clinical Radiology, vol. 43, no. 6, pp. 402–408, 1991. View at Publisher · View at Google Scholar · View at Scopus
  40. N. Y. Han, D. J. Sung, B. J. Park et al., “Imaging features of growing teratoma syndrome following a malignant ovarian germ cell tumor,” Journal of Computer Assisted Tomography, vol. 38, no. 4, pp. 551–557, 2014. View at Publisher · View at Google Scholar · View at Scopus
  41. R. Hariprasad, L. Kumar, D. Janga, S. Kumar, and M. Vijayaraghavan, “Growing teratoma syndrome of ovary,” International Journal of Clinical Oncology, vol. 13, no. 1, pp. 83–87, 2008. View at Publisher · View at Google Scholar · View at Scopus
  42. E. K. Outwater, E. S. Siegelman, and J. L. Hunt, “Ovarian teratomas: tumor types and imaging characteristics,” RadioGraphics, vol. 21, no. 2, pp. 475–490, 2001. View at Publisher · View at Google Scholar · View at Scopus
  43. K. A. P. Schultz, J. Petronio, A. Bendel, R. Patterson, and D. J. Vaughn, “PD0332991 (Palbociclib) for treatment of pediatric intracranial growing teratoma syndrome,” Pediatric Blood and Cancer, vol. 62, no. 6, pp. 1072–1074, 2015. View at Publisher · View at Google Scholar · View at Scopus
  44. A. S. Clark, T. B. Karasic, A. DeMichele et al., “Palbociclib (PD0332991)—a Selective and Potent Cyclin-Dependent Kinase Inhibitor: a review of pharmacodynamics and clinical development,” JAMA Oncology, vol. 2, no. 2, pp. 253–260, 2016. View at Publisher · View at Google Scholar
  45. D. J. Vaughn, K. Flaherty, P. Lal et al., “Treatment of growing teratoma syndrome,” New England Journal of Medicine, vol. 360, no. 4, pp. 423-424, 2009. View at Publisher · View at Google Scholar · View at Scopus
  46. V. Narayan, W.-T. Hwang, P. Lal et al., “Cyclin-Dependent Kinase 4/6 Inhibition for the Treatment of Unresectable Mature Teratoma: Long-Term Follow-Up of a Phase II Study,” Clinical Genitourinary Cancer, vol. 14, no. 6, pp. 504–510, 2016. View at Publisher · View at Google Scholar · View at Scopus
  47. Y.-L. Hsieh and C.-S. Liu, “Progression from an Immature Teratoma with Miliary Gliomatosis Peritonei to Growing Teratoma Syndrome with Nodular Gliomatosis Peritonei,” Pediatrics and Neonatology, vol. 50, no. 2, pp. 78–81, 2009. View at Publisher · View at Google Scholar · View at Scopus
  48. D. Lorusso, P. Malaguti, I. N. Trivellizzi, and G. Scambia, “Unusual liver locations of growing teratoma syndrome in ovarian malignant germ cell tumors,” Gynecologic Oncology Reports, vol. 1, no. 1, pp. 24-25, 2011. View at Publisher · View at Google Scholar · View at Scopus
  49. A. Pendlebury, D. Rischin, K. Ireland-Jenkin, G. C. Toner, and P. Grant, “Ovarian growing teratoma syndrome with spuriously elevated α-fetoprotein,” Journal of Clinical Oncology, vol. 33, no. 24, pp. e99–e100, 2015. View at Publisher · View at Google Scholar · View at Scopus
  50. M. Inoue, S. Hisasue, M. Nagae et al., “Interferon-α treatment for growing teratoma syndrome of the testis,” Case Reports in Nephrology and Urology, vol. 3, no. 1, pp. 40–45, 2013. View at Publisher · View at Google Scholar
  51. S. Postovsky, M. Epelbaum, O. B. Itzhak, D. Beck, and M. W. B. Arush, “Growing teratoma syndrome treated by interferon alpha-2β: Case report and literature review,” Pediatric Hematology and Oncology, vol. 21, no. 1, pp. 9–16, 2004. View at Publisher · View at Google Scholar · View at Scopus
  52. G. Rustin, E. S. Newlands, K. D. Bagshawe, S. B. Kaye, C. J. Williams, and J. L. Toy, “Response of differentiated but not anaplastic teratoma to interferon,” British Journal of Cancer, vol. 50, no. 5, pp. 611–616, 1984. View at Publisher · View at Google Scholar · View at Scopus
  53. J. Taylor-Papadimitriou, N. Ebsworth, and E. Rozengurt, “Possible mechanisms of interferon-induced growth inhibition,” Symposium on Fundamental Cancer Research, vol. 37, pp. 283–298, 1984. View at Google Scholar · View at Scopus
  54. J. Kattan, J.-P. Droz, S. Culine, P. Duvillard, A. Thiellet, and C. Peillon, “The growing teratoma syndrome: A woman with nonseminomatous germ cell tumor of the ovary,” Gynecologic Oncology, vol. 49, no. 3, pp. 395–399, 1993. View at Publisher · View at Google Scholar · View at Scopus
  55. A. Van der Gaast, T. C. Kok, and T. A. W. Splinter, “Growing teratoma syndrome successfully treated with lymphoblastoid interferon,” European Urology, vol. 19, no. 3, pp. 257-258, 1991. View at Google Scholar · View at Scopus
  56. G. Tzortzatos, A. Sioutas, and K. Schedvins, “Successful pregnancy after treatment for ovarian malignant teratoma with growing teratoma syndrome,” Fertility and Sterility, vol. 91, no. 3, pp. 936–e1, 2009. View at Publisher · View at Google Scholar · View at Scopus
  57. I. T. Yu, C. A. Griffin, P. C. Phillips et al., “Numerical sex chromosomal abnormalities in pineal teratomas by cytogenetic analysis and fluorescence in situ hybridization. Laboratory investigation,” Journal of Technical Methods and Pathology, vol. 72, pp. 419–423, 1995. View at Google Scholar
  58. J. Letourneau, S. W. Chan, and M. Rosen, “Accelerating ovarian age: Cancer treatment in the premenopausal woman,” Seminars in Reproductive Medicine, vol. 31, no. 6, pp. 462–468, 2013. View at Publisher · View at Google Scholar · View at Scopus