Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review

Figure 2

Histological findings: spleen angiosarcoma. At low-power field, histological sections revealed a large hemorrhagic areas with fibrin necrosis (H&E, 4x); at the periphery, foci of a solid vascular proliferation were evident (H&E, 10x). Spindle sarcomatoid cells with prominent hyperchromatic large elements characterized this high grade tumor. At high power field, atypical mitosis (arrow) and pseudovascular spaces were compatible with a final diagnosis of angiosarcoma (H&E, 40x).