Case Reports in Surgery / 2018 / Article / Tab 1

Case Report

Sclerosing Angiomatoid Nodular Transformation: Laparoscopic Splenectomy as Therapeutic and Diagnostic Approach at the Same Time

Table 1

Clinical features of 23 cases of SANT reported in literature.

AuthorNAgeGenderClinical featuresSpleen weightGross featuresFollow-upReferring dxConcurrent diseaseCore needle biopsy

Lee et al. [19]138FUpper abdominal discomfort associated with nausea5.1 × 4.7 cm, multiple tan well-defined nodules ranging from 0.8 cm to 1.2 cmSANT
Murthy et al. [6]156MLeft upper quadrant pain and mild anemia578 g17.5 × 11 × 9.5 cm, central bulky stellate mass of white compact tissue (5 × 4 × 4.5 cm)NED, 2 yearsSANTYes
Kakisaka et al. [7]136MNosebleed and anemia692 g13 cm in diameterSANT
Yoshimura et al. [20]256
Follow-up unenhanced CT
Medical checkup
Largest dimension of 6.5 cm
5.6 cm
Zhang et al. [14]13MAbdominal pain and vomiting 2 hours after being involved in a car accidentSolitary lesion, measuring 4 × 5 × 3 cmNED, 20 monthsSANT
Corrado et al. [8]137FPruritus in the lower limbs13 × 7 × 6 cm, with a solitary, well-circumscribed mass, measuring 5 cm in greatest diameter, with a multinodular fibrotic cut surfaceNED, 10 monthsSANTHomozygous mutation of methylene tetrahydrofolate reductase (MTHFR) and polymorphism of A1298C presented in the 19th week of gestation
Lim et al. [21]139MIncidental findings277.2 g11.0 × 9.0 × 7.0 cm; a well-circumscribed tumor measuring 5.0 × 4.5 × 4.5 cm was identifiedSANT
Bagul and Sen [22]124MPain in the left hypochondrium290 g12 × 10 × 8 cm, well-circumscribed tense lesion, dark red in color with interspersed stellate white projectionsSANT
Metin et al. [9]121MFatigue, weight loss, and abdominal pain for 4 months200 g11 × 8 × 7 cm, well-demarcated nodular lesion 3 × 2.5 × 2.3 cm in size at the hilumSANTYes
Zhou et al. [23]440
Incidental imaging studies

9.5 × 6.5 × 5.5 cm
8 × 6.5 × 5 cm
6 × 4 × 3 cm
5.5 × 5 × 4.5 cm
6 months, NED
9 months, NED
48 month, NED
8 months, NED
SANTLeft papillary thyroid carcinoma with metastasis to lymph nodes; multiple hepatic cysts; splenic mass
Hypertension; hepatitis A; multiple hepatic cysts; splenic mass
Hypertension; multiple hepatic cysts; nephric and splenic mass
Hypertension; diabetes; left nephric cysts; gallbladder polyps; mild fatty liver; splenic mass
Giorlandino et al. [24]171MIncidental imaging studies120 g10 × 7 × 2.5 cm, a 7 cm mass with an exophytic growth and a broad-based implant was observed at the superior pole−1 year, NEDSANT
Singh et al. [25]136MRoutine screening for abdominal pain100 gNodule measuring 1.5 cm in maximum dimension, located at the superior poleSANT
Kim et al. [26]123FIncidental imaging studiesSolitary mass, measuring 5.2 × 4.5 cmSANT
Nagai et al. [18]133MIncidental finding during follow-up after adrenalectomy for primary aldosteronismWell-demarcated, solitary lesion measuring 7 × 6.5 cmSANT
Wang et al. [27]129M1-year history of left upper quadrant and back discomfortWell-circumscribed mass measuring 7 cm in diameter13 monthsSANT
Cafferata et al. [17]157MMild left upper abdomen discomfort448 gA solitary, unencapsulated lesion (main diameter: 7 cm) with round, well-circumscribed borders10 monthsSANTFocal nodular hyperplasia and hemangioma of the liver
Aracil León et al. [28]155MIncidental finding during follow-up after renal abscess is resolved139 gA solitary, unencapsulated lesion (5.5 × 4 cm)15 monthsSANT
Martínez Martínez et al. [29]157FEpigastric abdominal pain and left hypochondrium painWell-delimited lesion in the addendum splenic tissue, 9 cm long from the major axisSANTDepression
Imamura et al. [30]137FIncidental imaging studies280 gWell-circumscribed 4.5 × 4 cm mass12 monthsSANT