Case Report
Primary Hepatic Lymphoma Mimicking a Hepatocellular Carcinoma in a Cirrhotic Patient: Case Report and Systematic Review of the Literature
| | Characteristics | |
| | Number | | | Age | 61.67 range(36–85) median: 61 y | | Sex | | | Male | 17 (51.5%) | | Female | 16 (48.5%) | | Presenting symptom | | | Asymptomatic | 21 (63.6%) | | Abdominal pain | 3 (9.1%) | | Elevated liver enzymes | 2 (6.1%) | | Generalized weakness | 1 (3%) | | Cough | 1 (3%) | | NA | 5 (15.2%) | | Preexisting liver disease | | | HCV | 7 (21.2%) | | HBV | 6 (18.2%) | | Primary biliary cirrhosis | 1 (3%) | | Old HAV | 1 (3%) | | None | 16 (48.5%) | | NA | 2 (7.1%) | | Cirrhosis | | | Yes | 7 (21.2%) | | No | 26 (78.8%) | | Associated HCC | 2 (6.1%) | | Number | 1.34 range(1–6) median 1 | | Size (cm) | 35.61 mm range(15–90) median: 30 mm | | Available MRI description | 6 (18.2%) | | Available CT scan description | 7 (21.2%) | | Available FDG PET | 5 (15.2%) | | Mean SUV max | 5.5 (3.5–8.2) | | Diagnosis | | | Preoperative biopsy | 15 (45.5%) | | After surgery | 16 (48.5%) | | NA | 2 (6.1%) | | Type of treatment | | | Resection | 12 (36.4%) | | Transplantation | 4 (12.1%) | | Chemotherapy | 6 (18.2%) | | Radiotherapy | 2 (6.1%) | | Surgery + chemotherapy | 5 (15.2%) | | Surgery + antiviral treatment | 1 (3%) | | Surgery + radiotherapy | 1 (3%) | | No treatment | 2 (6.1%) | | Outcome | | | Disease free survival at the last follow-up (9 months–5 years) | 21 (63.6%) | | Relapse at 30–51 months | 3 (9.1%) | | Death | 2 (6.1%) | | Lost to follow-up | 2 (6.1%) | | NA | 5 (15.2%) |
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NA: non available; HCV: hepatitis C virus; HBV: hepatitis B virus; HAV: hepatitis A virus; HCC: hepatocellular carcinoma; MRI: magnetic resonance imaging; CT: computed tomography; FDG PET: 2-deoxy-2[F-18]fluoro-D-glucose positron emission tomography; SUV: standardized uptake value.
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